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Huntington's Disease. (Photo compliments of Drs. E.C. Alvord, Jr., and A. E. Spence, Dept. of Pathology, University of Washington). Huntington's disease is a genetic disorder characterized by degeneration of neurons in the striatum, particularly the caudate nucleus. Typically it manifests as involuntary choreiform movements and, in later stages of the disease, as dementia. Arrows point to the severely atrophied caudate nucleus. The globus pallidus is present. The level of this coronal section is indicated by the presence of the anterior commissure (a portion of it is on the left side), and the optic chiasm in the midline.

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Software (C) 1997 <---> Images (C) 2000